Journal of Diabetes Research and Management

Insulin Resistance and Therapy

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Insulin is a vital hormone produced by the pancreas that controls blood glucose (sugar) levels. Insulin resistance, also called impaired insulin sensitivity, occurs when muscles, fat, and liver cells don’t react to insulin as they should. Insulin resistance can either be acute or persistent and is occasionally treatable. Even though excess body fat, physical inactivity, high-carbohydrate content diets, and certain medications such as steroids seem to induce insulin resistance, the exact mechanism for the development of resistance is yet to be revealed. Metformin is the prime medication used for treating diabetes, blood pressure medications, and statin administration to lower LDL cholesterol. Healthy eating habits, physical activity, and weight loss are cardinal in reversing insulin resistance.